Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941531 | 0.83 | KMT2A (0.45) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7222454 | 0.82 | KMT2A (0.46) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL6716155 | 0.79 | KMT2A (0.42) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL31405005 | 0.77 | ALDH1A1 (0.30) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5568957 | 0.76 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL23906780 | 0.75 | SCN4A (0.47) | ALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL27458128 | 0.75 | KMT2A (0.50) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL27733271 | 0.72 | MEN1 (0.44) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3355925 | 0.72 | MEN1 (0.45) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL27260304 | 0.72 | HTR1A (0.34) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |