Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386591 | 0.98 | KMT2A (0.51) | KMT2AMEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL8560879 | 0.88 | KDM4E (0.51) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8562390 | 0.86 | CYP2D6 (0.54) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8568373 | 0.84 | HRH3 (0.52) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL10387010 | 0.83 | ALDH1A1 (0.49) | KMT2AMEN1KDM4EALDH1A1TSHR | |
| SCHEMBL167209 | 0.82 | KMT2A (0.51) | KMT2AMEN1HPGDALDH1A1SIGMAR1 | |
| SCHEMBL8560399 | 0.82 | KMT2A (0.35) | KMT2AMEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL8568547 | 0.82 | KDM4E (0.47) | KMT2AMEN1KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL8565351 | 0.82 | ATM (0.54) | KMT2AMEN1KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL2254970 | 0.80 | KMT2A (0.50) | KMT2AMEN1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705497-A | INOTROPIC, ANTIARRHYTHMIA AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-01-06 | — | — | US | disclosed |