Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301323 | 0.89 | HRH3 (0.49) | ALDH1A1HRH3KDM4EPAOXRAB9A | |
| Hydrochloric Acid SCHEMBL1950623 | 0.87 | HRH3 (0.48) | ALDH1A1HRH3KDM4EPAOXRAB9A | |
| Hydrochloric Acid SCHEMBL3107158 | 0.84 | PAOX (0.53) | ALDH1A1HRH3KDM4EPAOXRAB9A | |
| SCHEMBL8564311 | 0.83 | KMT2A (0.49) | ALDH1A1HRH3KDM4EHTR1BPOLB | |
| SCHEMBL10388024 | 0.83 | HRH3 (0.46) | ALDH1A1HRH3KDM4EPAOXRAB9A | |
| SCHEMBL17387575 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HRH3KDM4EPAOXHTR1B | |
| SCHEMBL11858444 | 0.82 | SLC18A3 (0.51) | ALDH1A1HRH3KDM4EPAOXHTR1B | |
| SCHEMBL10386591 | 0.82 | KMT2A (0.51) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL11027681 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HRH3KDM4EPAOXHTR1B | |
| SCHEMBL9980789 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HRH3KDM4EPAOXHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958024-A | REACTION OF CARBAMATE SUBSTITUTED ACRYLIC ESTER, VASODILATORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4914227-A | FOR VASODILATING AND HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4739106-A | VASODILATION, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0101023-B1 | PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | disclosed |
| EP-0101023-A1 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-02-22 | — | — | EP | disclosed |