Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565124 | 0.81 | KDM4E (0.38) | MAPTGRM2POLBKDM1AMAPK1 | |
| SCHEMBL8562792 | 0.81 | MGMT (0.40) | MGMTMAPTCYP3A4KDM1AMAPK1 | |
| SCHEMBL8566327 | 0.78 | MGMT (0.38) | MGMTMAPTCYP3A4GRM2POLB | |
| SCHEMBL8567950 | 0.78 | CYP3A4 (0.47) | MGMTMAPTCYP3A4POLBMAPK1 | |
| SCHEMBL8566311 | 0.77 | MGMT (0.61) | MGMTMAPTMAPK1HTTLMNA | |
| SCHEMBL3953291 | 0.76 | KDM4E (0.52) | MGMTMAPTCYP3A4POLBMAPK1 | |
| SCHEMBL8562740 | 0.75 | MGMT (0.43) | MGMTMAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL8598122 | 0.74 | TLR8 (0.48) | MGMTMAPTCYP3A4KMT2AMEN1 | |
| SCHEMBL8567514 | 0.74 | S100A4 (0.54) | MGMTMAPTCYP3A4CDK5CDK5R1 | |
| SCHEMBL12518927 | 0.74 | MAOA (0.48) | MGMTMAPTCYP3A4MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |