Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567277 | 0.74 | HTR6 (0.35) | MAPTRECQLMKNK1MKNK2HRH4 | |
| SCHEMBL6672459 | 0.74 | MAPT (0.47) | MAPTRECQLCYP3A4ALDH1A1HTR6 | |
| SCHEMBL25199417 | 0.71 | IGF1R (0.38) | MAPTCDK2CYP3A4CYP2C9PRKCQ | |
| SCHEMBL21081167 | 0.71 | HTR2C (0.46) | MKNK1MKNK2TLR9TLR8TLR7 | |
| SCHEMBL8560822 | 0.71 | MEN1 (0.43) | MAPTMKNK1MKNK2ALDH1A1HTR6 | |
| SCHEMBL23047424 | 0.71 | NOS3 (0.44) | MKNK1MKNK2CDK2TLR9TLR8 | |
| SCHEMBL8564866 | 0.70 | EGFR (0.41) | MAPTRECQLCYP3A4CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6493109 | 0.70 | MAPT (0.45) | MAPTRECQLCYP3A4ALDH1A1HTR6 | |
| Hydrochloric Acid SCHEMBL21045940 | 0.70 | HTR2C (0.47) | MKNK1MKNK2TLR9TLR8TLR7 | |
| SCHEMBL8567927 | 0.70 | PIM1 (0.36) | MAPTRECQLCDK2TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |