Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748376 | 0.78 | HTR2C (0.51) | MEN1KMT2AHTTMAPTHTR2C | |
| SCHEMBL793501 | 0.76 | MEN1 (0.51) | MEN1KMT2ARPS6KA3ALDH1A1HTT | |
| SCHEMBL14521403 | 0.72 | MEN1 (0.75) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL24610442 | 0.72 | RPS6KA3 (0.44) | RPS6KA3MKNK1MKNK2HTR2CHRH3 | |
| SCHEMBL8567927 | 0.72 | PIM1 (0.36) | RPS6KA3MAPTHTR2CHRH3GABRA1 | |
| Hydrochloric Acid SCHEMBL4091933 | 0.71 | IKBKB (0.48) | MEN1KMT2AMKNK1MKNK2CHUK | |
| SCHEMBL8564380 | 0.71 | MAPT (0.36) | MEN1KMT2AMKNK1MKNK2ALDH1A1 | |
| SCHEMBL8561395 | 0.70 | HTR1A (0.49) | HTR2C | |
| SCHEMBL8561865 | 0.70 | MAPT (0.44) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL20191065 | 0.70 | MEN1 (0.46) | MEN1KMT2AALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |