Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ATIC | P31939 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567404 | 0.85 | KMT2A (0.45) | ALDH1A1CYP2C19CYP1A2CYP2C9ALOX15 | |
| SCHEMBL8560933 | 0.80 | ALDH1A1 (0.51) | ALDH1A1CYP2C19CYP1A2CYP2C9ALOX15 | |
| SCHEMBL27542356 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KMT2AKDM4EPOLBGAA | |
| SCHEMBL8566984 | 0.78 | CA1 (0.39) | ALDH1A1CYP1A2CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL8602040 | 0.78 | KMT2A (0.42) | ALDH1A1CYP1A2CYP2C9CYP3A4KMT2A | |
| SCHEMBL8566513 | 0.78 | CASP6 (0.44) | ALDH1A1CYP3A4CASP6KMT2ASMN1; SMN2 | |
| SCHEMBL8562398 | 0.77 | CYP19A1 (0.51) | ALDH1A1KDM4EGLAMAPTMAPK1 | |
| SCHEMBL8775745 | 0.77 | RCE1 (0.47) | ALDH1A1CYP2C19CYP1A2CYP2C9ALOX15 | |
| SCHEMBL8598916 | 0.76 | TXNRD1 (0.44) | ALDH1A1CYP2C19CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL8623968 | 0.76 | MAPT (0.37) | ALDH1A1KMT2ASMN1; SMN2KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |