Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131601 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8557711 | 0.78 | LMNA (0.39) | LMNA | |
| SCHEMBL8565270 | 0.77 | MITF (0.31) | — | |
| SCHEMBL8564887 | 0.74 | TAAR1 (0.35) | — | |
| SCHEMBL6131614 | 0.71 | LMNA (0.52) | LMNA | |
| SCHEMBL6131607 | 0.70 | MITF (0.40) | LMNA | |
| SCHEMBL8565364 | 0.69 | LMNA (0.39) | LMNA | |
| SCHEMBL8478713 | 0.68 | LMNA (0.51) | LMNAALDH1A1 | |
| SCHEMBL8741531 | 0.68 | LMNA (0.36) | LMNA | |
| SCHEMBL6131605 | 0.67 | CA12 (0.46) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808091-A | DIAGNOSTIC IMAGING AGENT | BRACCO INTERNATIONAL B.V. | 1998-09-15 | — | — | US | disclosed |
| US-5688487-A | Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 1997-11-18 | — | — | US | disclosed |