Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 3/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936538 | 0.79 | ALDH1A1 (0.41) | HTTHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL31481284 | 0.79 | GPR35 (0.41) | HTTHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL28802588 | 0.77 | MEN1 (0.41) | HTTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL3688848 | 0.76 | MAPT (0.47) | HTTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL8559928 | 0.76 | MAPT (0.40) | HTTHSD17B10MEN1USP2KMT2A | |
| SCHEMBL4756003 | 0.76 | ALDH1A1 (0.35) | HTTHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL18486948 | 0.74 | KMT2A (0.42) | HTTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL8561095 | 0.74 | MEN1 (0.42) | HTTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL4064206 | 0.73 | MEN1 (0.41) | HTTHSD17B10MEN1USP2KMT2A | |
| SCHEMBL414810 | 0.73 | MEN1 (0.41) | HTTMEN1USP2KMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |