Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31539695 | 0.76 | GRIN2D (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3936538 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8564751 | 0.76 | HTT (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL31481284 | 0.76 | GPR35 (0.41) | ALDH1A1MAPTKDM4EMEN1RECQL | |
| SCHEMBL8569914 | 0.76 | MAPT (0.42) | ALDH1A1MAPTKDM4EMEN1RECQL | |
| SCHEMBL31092325 | 0.76 | VCAM1 (0.44) | ALDH1A1MAPTKDM4EMEN1RECQL | |
| SCHEMBL1721407 | 0.73 | EGLN2 (0.37) | MAPTKDM4EHTTHSD17B10LMNA | |
| SCHEMBL25297122 | 0.71 | KDM4E (0.33) | ALDH1A1KDM4EKMT2ATDP1HTT | |
| SCHEMBL16127588 | 0.71 | SLC22A12 (0.41) | ALDH1A1VCAM1TDP1 | |
| SCHEMBL3237039 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MAPTVCAM1GRM6GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119015-A2 | SYNTHESIS OF THIOHYDANTOINS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2008-10-02 | — | — | WO | disclosed |