Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596337 | 0.87 | LMNA (0.48) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7590944 | 0.84 | KDM4E (0.43) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8564794 | 0.80 | LMNA (0.38) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8380413 | 0.78 | LMNA (0.49) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8417990 | 0.77 | LMNA (0.39) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8562051 | 0.77 | LMNA (0.46) | LMNACYP2C19HIF1A | |
| SCHEMBL9513442 | 0.76 | LMNA (0.55) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL619959 | 0.76 | LMNA (0.58) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL8380052 | 0.75 | KDM4E (0.44) | LMNACYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL905517 | 0.75 | KDM4E (0.48) | LMNACYP2C19HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782564-B1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-09-01 | — | — | EP | disclosed |