Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564876 | 1.00 | KDM4E (0.49) | KDM4EHSD17B10FDFT1LPAR1CRHR1 | |
| SCHEMBL6957617 | 0.83 | KDM4E (0.44) | KDM4EFDFT1LPAR1ALDH1A1LMNA | |
| SCHEMBL9727045 | 0.82 | FDFT1 (0.43) | KDM4EFDFT1LPAR1MAPTALDH1A1 | |
| SCHEMBL8561511 | 0.82 | KDM4E (0.45) | KDM4EHSD17B10LPAR1CRHR1HSP90AA1 | |
| SCHEMBL8799319 | 0.80 | ADRB2 (0.44) | FDFT1LPAR1MAPTALDH1A1 | |
| SCHEMBL2737368 | 0.77 | KDM4E (0.58) | KDM4EHSD17B10LPAR1MAPTLMNA | |
| SCHEMBL4129117 | 0.77 | LPAR1 (0.38) | KDM4EFDFT1LPAR1MAPTALDH1A1 | |
| SCHEMBL8799234 | 0.77 | FDFT1 (0.42) | FDFT1LMNASMN1; SMN2POLB | |
| SCHEMBL28742134 | 0.76 | KDM4E (0.54) | KDM4EHSD17B10LPAR1HSP90AA1HSP90AB1 | |
| SCHEMBL8118267 | 0.76 | FDFT1 (0.48) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770438-A | CHEMICAL INTERMEDIATES FOR ANTICHOLESTEROL COMPOUNDS, CYCLIZATION TO FORM BENZOXAZEPINE OR BENZOTHIAZEPINE COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0710725-A1 | Production of optically active compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |