Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567126 | 1.00 | MAPT (0.39) | MAPTMGMTCYP3A4RAB9ANPC1 | |
| SCHEMBL8562134 | 0.86 | NFE2L2 (0.41) | MAPTMGMTCYP3A4RAB9ANPC1 | |
| SCHEMBL8567366 | 0.82 | KDM4E (0.40) | MAPTCYP3A4RAB9ANPC1KMT2A | |
| SCHEMBL8567364 | 0.82 | KDM4E (0.40) | MAPTCYP3A4RAB9ANPC1KMT2A | |
| SCHEMBL8564990 | 0.80 | MGMT (0.39) | MAPTMGMTKMT2AMEN1MAPK1 | |
| SCHEMBL8564994 | 0.80 | MGMT (0.39) | MAPTMGMTKMT2AMEN1MAPK1 | |
| SCHEMBL8563099 | 0.79 | ALDH1A1 (0.40) | MAPTCYP3A4RAB9ANPC1KMT2A | |
| SCHEMBL8563097 | 0.79 | ALDH1A1 (0.40) | MAPTCYP3A4RAB9ANPC1KMT2A | |
| SCHEMBL8567950 | 0.79 | CYP3A4 (0.47) | MAPTMGMTCYP3A4RAB9AKMT2A | |
| SCHEMBL12518927 | 0.78 | MAOA (0.48) | MAPTMGMTCYP3A4RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |