SCHEMBL8565060 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CA1	P00915	10/20	0.39

▸	CA2	P00918	10/20	0.39

▸	CA9	Q16790	8/20	0.39

▸	CA12	O43570	7/20	0.39

▸	CAPN9	O14815	1/20	0.39

▸	TRPM8	Q7Z2W7	1/20	0.37

▸	MAPT	P10636	1/20	0.36

▸	PPM1B	O75688	1/20	0.34

▸	PTPN1	P18031	1/20	0.34

▸	PPP1CC	P36873	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11375660	1.00	CA1 (0.39)	CA1CA2CA9CA12CAPN9
SCHEMBL25941269	0.86	CA1 (0.38)	CA1CA2CA9CA12CAPN9
SCHEMBL19321646	0.85	TRPM8 (0.45)	CA1CA2CA9CA12CAPN9
SCHEMBL19321648	0.85	TRPM8 (0.45)	CA1CA2CA9CA12CAPN9
SCHEMBL13748535	0.85	TRPM8 (0.45)	CA1CA2CA9CA12CAPN9
SCHEMBL22869421	0.85	TRPM8 (0.45)	CA1CA2CA9CA12CAPN9
SCHEMBL24895109	0.83	CAPN9 (0.40)	CA1CA2CA9CA12CAPN9
SCHEMBL18891702	0.81	CAPN9 (0.39)	CA1CA2CA9CA12CAPN9
SCHEMBL1030989	0.81	CA1 (0.38)	CA1CA2CA9CA12CAPN9
SCHEMBL19557124	0.79	CA1 (0.37)	CA1CA2CA9CA12CAPN9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5731432-A	Inhibitors of adenosine monophosphate deaminase	GENSIA SICOR INC. (US)	1998-03-24	—	—	US	disclosed