Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 3/20 | 0.35 |
| ▸ | F3 | P13726 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571879 | 0.90 | FAAH (0.35) | FAAHTRPV1F7F3MMP2 | |
| SCHEMBL8563168 | 0.80 | TRPV1 (0.38) | FAAHTRPV1 | |
| SCHEMBL8565144 | 0.79 | CNR2 (0.42) | MAPT | |
| SCHEMBL8571303 | 0.76 | FAAH (0.36) | FAAHCYSLTR2CYSLTR1ASAH2 | |
| SCHEMBL8571237 | 0.75 | CNR2 (0.41) | — | |
| SCHEMBL8669761 | 0.74 | ALDH1A1 (0.52) | KDM4EMAPTHSD17B10ASAH2 | |
| SCHEMBL8565168 | 0.74 | ALDH1A1 (0.52) | KDM4EMAPTHSD17B10ASAH2 | |
| SCHEMBL8571151 | 0.74 | RARB (0.51) | KDM4EMAPTHSD17B10ASAH2 | |
| SCHEMBL8668785 | 0.74 | RARB (0.51) | KDM4EMAPTHSD17B10ASAH2 | |
| SCHEMBL8566599 | 0.72 | PPARA (0.38) | FAAHASAH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |