SCHEMBL8563168

SCHEMBL8563168

CCCCCCCCCCOc1cc(-c2ncccn2)ccc1C=CCCCC(C)O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.38
PTPN11 Q06124 3/20 0.35
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
P2RY12 Q9H244 1/20 0.35
SMPD1 P17405 1/20 0.35
FAAH O00519 1/20 0.35
PPARG P37231 4/20 0.34
PPARA Q07869 2/20 0.34
TLR8 Q9NR97 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8571237 0.80 CNR2 (0.41) PTPN11SMPD1
SCHEMBL8565172 0.80 FAAH (0.39) TRPV1FAAH
SCHEMBL8565144 0.79 CNR2 (0.42) PTPN11SMPD1
SCHEMBL8570086 0.76 ALDH1A1 (0.37) PTPN11SMPD1PPARGPPARA
SCHEMBL8600108 0.74 MAPT (0.31)
SCHEMBL8049551 0.74 RAB9A (0.41)
SCHEMBL8044578 0.74 RAB9A (0.41)
SCHEMBL8052519 0.74 RAB9A (0.41)
SCHEMBL8052513 0.74 RAB9A (0.41)
SCHEMBL8049555 0.74 RAB9A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed