Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600371 | 0.75 | TNKS2 (0.53) | TNKS2DDAH1ADORA3ADORA2AADORA1 | |
| SCHEMBL8576858 | 0.72 | PARP1 (0.48) | ALDH1A1PARP1TLR7KDM4EGAA | |
| SCHEMBL5502915 | 0.71 | TLR7 (0.31) | TNKS2POLBTLR7 | |
| SCHEMBL8576955 | 0.69 | KMT2A (0.44) | ALDH1A1PARP1KDM4EGAAMEN1 | |
| SCHEMBL8572046 | 0.68 | GAA (0.46) | TNKS2ADORA3ALDH1A1GLASMN1; SMN2 | |
| SCHEMBL6737901 | 0.67 | ELANE (0.40) | GLAPARP1TLR7KDM4EGAA | |
| SCHEMBL8575152 | 0.66 | JAK2 (0.41) | ADORA3POLBPARP1TLR7KDM4E | |
| SCHEMBL4065218 | 0.65 | ADORA1 (0.36) | ADORA3ADORA2AADORA1TLR7KDM4E | |
| SCHEMBL9036182 | 0.65 | TLR7 (0.52) | ADORA3ADORA2AADORA1ALDH1A1PARP1 | |
| SCHEMBL30176850 | 0.64 | TNKS2 (1.00) | TNKS2DDAH1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641342-B1 | ANTIVIRAL 2-ETHYL-1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES | MINNESOTA MINING & MFG (US) | 1998-08-05 | — | — | EP | disclosed |