Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 4/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ESRRB | O95718 | 1/20 | 0.30 |
| ▸ | ESRRA | P11474 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068203 | 0.85 | KDM4E (0.36) | TLR7KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL6737901 | 0.70 | ELANE (0.40) | TLR7KDM4E | |
| SCHEMBL5510125 | 0.66 | ELANE (0.39) | KDM4EMAPT | |
| SCHEMBL6221678 | 0.65 | DPP4 (0.40) | KDM4EHPGDPDE3BPDE3A | |
| SCHEMBL8565234 | 0.65 | TNKS2 (0.46) | ADORA1ADORA3ADORA2ATLR7KDM4E | |
| SCHEMBL4063897 | 0.64 | ALOX5 (0.34) | ADORA1ADORA3ADORA2AKDM4EHPGD | |
| SCHEMBL20970190 | 0.64 | RAD52 (0.43) | TLR7KDM4EMAPT | |
| SCHEMBL19513287 | 0.64 | PTGES (0.44) | ADORA1ADORA3ADORA2ATLR7 | |
| SCHEMBL4586845 | 0.64 | TLR8 (0.36) | ADORA1ADORA3ADORA2ATLR7ADORA2B | |
| SCHEMBL8852871 | 0.62 | DYRK1A (0.52) | KDM4EHPGDHSD17B10PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673087-A4 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1673087-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005032484-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |