Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576858 | 0.86 | PARP1 (0.48) | JAK2TLR8KDM4EPARP1TLR7 | |
| SCHEMBL8576955 | 0.79 | KMT2A (0.44) | KDM4EPARP1MAPT | |
| SCHEMBL8572046 | 0.77 | GAA (0.46) | ADORA3MAOAKDM4EPARP1MAPT | |
| SCHEMBL19475356 | 0.70 | RAD52 (0.43) | TLR8TERTPARP1TLR7POLB | |
| SCHEMBL5502915 | 0.70 | TLR7 (0.31) | TLR7POLB | |
| SCHEMBL8565234 | 0.66 | TNKS2 (0.46) | ADORA3KDM4EPARP1TLR7POLB | |
| SCHEMBL6795539 | 0.65 | PARP1 (0.69) | PARP1POLBPARP2 | |
| SCHEMBL9038851 | 0.65 | PARP1 (0.57) | TLR8PARP1TLR7 | |
| SCHEMBL31104462 | 0.65 | HTR6 (0.47) | JAK2TERTKDM4EPOLB | |
| SCHEMBL4586845 | 0.64 | TLR8 (0.36) | TLR8ADORA3TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741909-A | PHARMACEUTICAL COMPOSITIONS WHICH ACT AS ANTIVIRAL AGENTS, INDUCE BIOSYNTHESIS OF INTERFERON AND INHIBIT TUMOR FORMATION IN ANIMALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |