Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566551 | 0.86 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1KDM4EKMT2A | |
| SCHEMBL8569903 | 0.84 | MAPK1 (0.34) | ALDH1A1LMNATDP1KDM4EKMT2A | |
| SCHEMBL8566844 | 0.80 | MEN1 (0.40) | ALDH1A1LMNATDP1KMT2APOLB | |
| SCHEMBL8562112 | 0.77 | GAA (0.41) | ALDH1A1LMNATDP1KMT2AL3MBTL1 | |
| SCHEMBL29081731 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNATDP1SIRT3KMT2A | |
| SCHEMBL8568707 | 0.75 | CES2 (0.39) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL8600107 | 0.74 | KDM4E (0.36) | ALDH1A1LMNAKDM4ECYP3A4SMN1; SMN2 | |
| SCHEMBL8603015 | 0.74 | ATG4B (0.43) | ALDH1A1KMT2APOLBCYP3A4SMN1; SMN2 | |
| SCHEMBL8568617 | 0.73 | MAPK1 (0.38) | ALDH1A1LMNAKMT2APOLBSMN1; SMN2 | |
| SCHEMBL8565256 | 0.73 | MAPT (0.41) | ALDH1A1LMNATDP1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |