Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564837 | 0.84 | HRH3 (0.35) | ALDH1A1SIGMAR1POLBACHEHRH3 | |
| SCHEMBL4912846 | 0.73 | ALDH1A1 (0.38) | KEAP1SMN1; SMN2KDM4EALDH1A1GLA | |
| SCHEMBL28213261 | 0.71 | — | — | |
| SCHEMBL11565842 | 0.70 | KEAP1 (0.44) | KEAP1SMN1; SMN2KDM4EALDH1A1USP2 | |
| SCHEMBL28199430 | 0.69 | — | — | |
| SCHEMBL10916903 | 0.69 | KDM4E (0.55) | KEAP1SMN1; SMN2KDM4EALDH1A1USP2 | |
| SCHEMBL416345 | 0.69 | SMN1; SMN2 (0.50) | KEAP1SMN1; SMN2KDM4EALDH1A1USP2 | |
| SCHEMBL28142359 | 0.69 | KEAP1 (0.42) | KEAP1SMN1; SMN2KDM4EALDH1A1GLA | |
| SCHEMBL29788395 | 0.69 | SMN1; SMN2 (0.45) | KEAP1SMN1; SMN2KDM4EALDH1A1USP2 | |
| SCHEMBL235080 | 0.68 | KDM4E (0.65) | KEAP1SMN1; SMN2KDM4EALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |