Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565322 | 0.84 | KEAP1 (0.41) | HRH3ACHESIGMAR1CHRM2CHRM1 | |
| SCHEMBL28213261 | 0.72 | — | — | |
| SCHEMBL4903211 | 0.72 | CXCR4 (0.37) | HRH3CXCR4TERTSIGMAR1LMNA | |
| SCHEMBL28199430 | 0.71 | — | — | |
| SCHEMBL5551787 | 0.69 | — | — | |
| SCHEMBL28078047 | 0.68 | CXCR4 (0.60) | HRH3CXCR4SIGMAR1CHRM2CHRM1 | |
| SCHEMBL6913246 | 0.68 | CXCR4 (0.60) | HRH3CXCR4SIGMAR1CHRM2CHRM1 | |
| SCHEMBL1914465 | 0.68 | CXCR4 (0.60) | HRH3CXCR4SIGMAR1CHRM2CHRM1 | |
| SCHEMBL28131682 | 0.67 | — | — | |
| SCHEMBL7998614 | 0.67 | CXCR4 (0.48) | HRH3CXCR4SIGMAR1LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |