Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 9/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103372 | 0.82 | SLC18A3 (0.40) | SLC6A2SLC6A4SLC18A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8571208 | 0.81 | KDM1A (0.40) | SLC6A2SLC6A4SLC18A3SIGMAR1 | |
| SCHEMBL8562015 | 0.78 | TNKS (0.36) | TNKS2SLC18A3SIGMAR1TNKSNSD3 | |
| SCHEMBL8568450 | 0.74 | KDM1A (0.38) | SLC6A2SLC6A4SLC6A3SLC18A3SIGMAR1 | |
| SCHEMBL6167647 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A3TNKS2HTR6 | |
| SCHEMBL1198050 | 0.69 | MAPK1 (0.44) | — | |
| SCHEMBL8570694 | 0.69 | PARP1 (0.49) | SIGMAR1 | |
| SCHEMBL2606251 | 0.68 | GSK3B (0.40) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6168112 | 0.68 | HTR2C (0.50) | — | |
| Hydrochloric Acid SCHEMBL2322170 | 0.68 | MAPK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |