Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | PRKCG | P05129 | 2/20 | 0.43 |
| ▸ | PRKCB | P05771 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.43 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.43 |
| ▸ | STK16 | O75716 | 1/20 | 0.43 |
| ▸ | PAK3 | O75914 | 1/20 | 0.43 |
| ▸ | CDK14 | O94921 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445321 | 0.86 | OPRL1 (0.52) | OPRM1OPRK1OPRL1CYP2C19KMT2A | |
| SCHEMBL6168606 | 0.86 | OPRL1 (0.52) | OPRM1OPRK1OPRL1CYP2C19KMT2A | |
| SCHEMBL8565096 | 0.85 | CCR5 (0.48) | TRPV6SIGMAR1OPRL1CHRM2CHRM3 | |
| SCHEMBL8573015 | 0.84 | PARP1 (0.51) | PARP1KDM4EPRKG1OPRL1ALDH1A1 | |
| SCHEMBL8569508 | 0.82 | MEN1 (0.53) | SIGMAR1OPRM1OPRL1KMT2ACXCR3 | |
| SCHEMBL8570739 | 0.82 | CHRM2 (0.54) | TRPV6KDM4ESIGMAR1GSK3BOPRM1 | |
| SCHEMBL8564971 | 0.81 | TACR1 (0.43) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL8565287 | 0.81 | CHRM3 (0.53) | SIGMAR1OPRM1KMT2AALDH1A1CHRM1 | |
| SCHEMBL6168284 | 0.81 | TACR1 (0.41) | KDM4ESMN1; SMN2OPRM1OPRL1KMT2A | |
| SCHEMBL6168102 | 0.80 | CHRM3 (0.42) | PARP1PRKCGPRKCBPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |