Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 8/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103372 | 0.85 | SLC18A3 (0.40) | KDM1ASLC18A3SIGMAR1ATMMEN1 | |
| Hydrochloric Acid SCHEMBL8571208 | 0.84 | KDM1A (0.40) | KDM1ASLC18A3SIGMAR1ATMMEN1 | |
| SCHEMBL8565038 | 0.83 | CHRM3 (0.47) | SIGMAR1 | |
| SCHEMBL8564511 | 0.81 | CCR5 (0.36) | TNKSTNKS2SIGMAR1BRD4TP53 | |
| SCHEMBL8565402 | 0.78 | HTR1A (0.40) | TNKSTNKS2SLC18A3SIGMAR1NSD3 | |
| SCHEMBL8568450 | 0.78 | KDM1A (0.38) | KDM1ASLC18A3SIGMAR1ATMMEN1 | |
| SCHEMBL8573043 | 0.77 | SIGMAR1 (0.43) | KDM1ASIGMAR1 | |
| SCHEMBL6167647 | 0.77 | SLC6A2 (0.38) | TNKS2ATMTP53MEN1KMT2A | |
| SCHEMBL8570094 | 0.74 | CHRM3 (0.51) | SIGMAR1KMT2APOLB | |
| SCHEMBL8565096 | 0.73 | CCR5 (0.48) | KDM1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |