Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420308 | 0.99 | FDFT1 (0.65) | FDFT1L3MBTL1MAPK1HRH3LMNA | |
| SCHEMBL8772635 | 0.84 | FDFT1 (0.46) | FDFT1L3MBTL1MAPK1LMNAALDH1A1 | |
| SCHEMBL8772603 | 0.83 | FDFT1 (0.45) | FDFT1L3MBTL1MAPK1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8772602 | 0.81 | FDFT1 (0.42) | FDFT1L3MBTL1LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8421585 | 0.81 | FDFT1 (0.41) | FDFT1GABRA1GABRB2KMT2AKDM4E | |
| SCHEMBL8423284 | 0.81 | FDFT1 (0.41) | FDFT1MAPK1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL8968715 | 0.79 | FDFT1 (1.00) | FDFT1 | |
| SCHEMBL9150829 | 0.79 | FDFT1 (0.41) | FDFT1MAPK1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL8422017 | 0.78 | FDFT1 (0.39) | FDFT1L3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL8772588 | 0.78 | PTGDR (0.39) | FDFT1LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |