Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168075 | 0.95 | CHRM3 (0.50) | CHRM2CHRM3SIGMAR1CYP2D6CYP2C9 | |
| SCHEMBL29445321 | 0.91 | OPRL1 (0.52) | CHRM2CHRM3CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6168606 | 0.91 | OPRL1 (0.52) | CHRM2CHRM3CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6167277 | 0.90 | CHRM3 (0.53) | CHRM2CHRM3SIGMAR1CYP2D6CYP2C9 | |
| SCHEMBL8564439 | 0.89 | CHRM2 (0.55) | CHRM2CHRM3SIGMAR1CYP2D6CYP2C9 | |
| SCHEMBL6168220 | 0.89 | CHRM2 (0.49) | CHRM2CHRM3SIGMAR1CYP2D6CYP2C9 | |
| SCHEMBL8569557 | 0.88 | CHRM2 (0.54) | CHRM2CHRM3ALDH1A1KMT2AOPRL1 | |
| SCHEMBL8571871 | 0.88 | CHRM3 (0.54) | CHRM2CHRM3SIGMAR1OPRL1 | |
| SCHEMBL8562946 | 0.88 | CHRM3 (0.54) | CHRM2CHRM3OPRL1 | |
| SCHEMBL8570520 | 0.88 | OPRL1 (0.45) | CHRM2CHRM3OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |