Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.54 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168606 | 0.91 | OPRL1 (0.52) | CHRM2CHRM3DRD4DRD2DRD3 | |
| SCHEMBL29445321 | 0.91 | OPRL1 (0.52) | CHRM2CHRM3DRD4DRD2DRD3 | |
| SCHEMBL8570520 | 0.90 | OPRL1 (0.45) | CHRM2CHRM3DRD4DRD2DRD3 | |
| SCHEMBL8564439 | 0.89 | CHRM2 (0.55) | CHRM2CHRM3DRD4DRD2DRD3 | |
| SCHEMBL5100221 | 0.88 | OPRL1 (0.44) | CHRM2CHRM3DRD4DRD2DRD3 | |
| SCHEMBL8562946 | 0.88 | CHRM3 (0.54) | CHRM2CHRM3ACHEOPRL1OPRM1 | |
| SCHEMBL8571871 | 0.88 | CHRM3 (0.54) | CHRM2CHRM3DRD2DRD3BACE1 | |
| SCHEMBL6164748 | 0.88 | OPRL1 (0.44) | CHRM2CHRM3DRD2ACHEOPRL1 | |
| SCHEMBL8565541 | 0.88 | CHRM2 (0.54) | CHRM2CHRM3KMT2AOPRL1ALDH1A1 | |
| SCHEMBL8565802 | 0.87 | MEN1 (0.45) | CHRM2CHRM3DRD4DRD2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |