Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445321 | 0.91 | OPRL1 (0.52) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL6168606 | 0.91 | OPRL1 (0.52) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL8564439 | 0.89 | CHRM2 (0.55) | CHRM3CHRM2OPRL1OPRM1 | |
| SCHEMBL8570520 | 0.88 | OPRL1 (0.45) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL8571871 | 0.88 | CHRM3 (0.54) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL8569557 | 0.88 | CHRM2 (0.54) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL8565541 | 0.88 | CHRM2 (0.54) | CHRM3CHRM2OPRL1 | |
| SCHEMBL6164748 | 0.88 | OPRL1 (0.44) | CHRM3CHRM2OPRL1ACHEOPRM1 | |
| SCHEMBL8564098 | 0.87 | OPRK1 (0.50) | F2F10PRSS1OPRM1 | |
| SCHEMBL5100221 | 0.86 | OPRL1 (0.44) | CHRM3CHRM2OPRL1ACHEOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |