Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168606 | 1.00 | OPRL1 (0.52) | OPRL1CHRM3CHRM2ACHEOPRM1 | |
| SCHEMBL6168165 | 0.93 | CHRM3 (0.49) | OPRL1CHRM3CHRM2ACHEOPRM1 | |
| SCHEMBL8569508 | 0.93 | MEN1 (0.53) | OPRL1CHRM3CHRM2ACHEOPRM1 | |
| SCHEMBL8570369 | 0.93 | CHRM3 (0.50) | OPRL1CHRM3CHRM2ACHEOPRM1 | |
| SCHEMBL8565096 | 0.92 | CCR5 (0.48) | OPRL1CHRM3CHRM2ACHECCR5 | |
| SCHEMBL6167277 | 0.92 | CHRM3 (0.53) | OPRL1CHRM3CHRM2ACHEDRD2 | |
| SCHEMBL8564439 | 0.92 | CHRM2 (0.55) | OPRL1CHRM3CHRM2OPRM1DRD2 | |
| SCHEMBL8562946 | 0.91 | CHRM3 (0.54) | OPRL1CHRM3CHRM2ACHEOPRM1 | |
| SCHEMBL8571871 | 0.91 | CHRM3 (0.54) | OPRL1CHRM3CHRM2ACHEOPRM1 | |
| SCHEMBL8569557 | 0.91 | CHRM2 (0.54) | OPRL1CHRM3CHRM2ACHEOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279672-B2 | Asymmetric synthesis of alpha-branched chiral amines | PIRAMAL PHARMA LIMITED (IN) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279672-B2 | Asymmetric synthesis of alpha-branched chiral amines | SLC6A12, BET1, BCAT2 | OPRL1 1730/4885CHRM3 1114/4885CHRM2 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.