Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL9649979 | 0.99 | AGTR2 (0.71) | AGTR2AGTR1 | |
| SCHEMBL9406616 | 0.99 | AGTR2 (0.71) | AGTR2AGTR1 | |
| Ammonia Solution, Strong SCHEMBL8972558 | 0.99 | AGTR2 (0.71) | AGTR2AGTR1 | |
| SCHEMBL9406623 | 0.99 | AGTR2 (0.71) | AGTR2AGTR1 | |
| SCHEMBL9649960 | 0.99 | AGTR2 (0.71) | AGTR2AGTR1 | |
| SCHEMBL8161625 | 0.95 | AGTR1 (0.65) | AGTR2AGTR1 | |
| Ammonia Solution, Strong SCHEMBL8971992 | 0.94 | AGTR1 (0.64) | AGTR2AGTR1 | |
| SCHEMBL8567083 | 0.93 | AGTR1 (0.61) | AGTR2AGTR1 | |
| SCHEMBL8972949 | 0.91 | AGTR2 (0.59) | AGTR2AGTR1 | |
| SCHEMBL8972186 | 0.91 | AGTR2 (0.59) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598702-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1994-05-25 | — | — | EP | claimed |
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | claimed |
| JP-3236377-A | — | — | None | — | — | JP | disclosed |
| EP-0598702-B1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | EISAI CO LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| EP-0628557-B1 | Biphenylmethane derivatives, the use of them and pharmacological compositions containing same | EISAI CO LTD (JP) | 1997-05-02 | — | — | EP | disclosed |
| US-5506238-A | HYPOTENSIVE AGENT | EISAI CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0420237-B1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | EISAI CO LTD (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0628557-A1 | Biphenylmethane derivatives, the use of them and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5332744-A | Hypotensive, congestive heart failure, intraocular pressure | MERCK & CO., INC. (US) | 1994-07-26 | — | — | US | disclosed |
| US-5328911-A | Cardiovascular disorders, hypotensive agents and congestive heart failure | EISAI CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0598702-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5298518-A | Biphenylmethane derivative and pharmacological use | EISAI CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5087702-A | Fermentation of streptomyces in the presence of angiotensin II receptor antagonist | MERCK & CO., INC. (US) | 1992-02-11 | — | — | US | disclosed |
| US-5066586-A | Fermenting 3-((2'-tetrazol-5-yl-biphenyl-4-yl)methyl)-7-methyl-2-propyl-3H-imidazo(4,5 -B)pyridine to oxidize | MERCK & CO., INC. (US) | 1991-11-19 | — | — | US | disclosed |
| JP-H03236377-A | CONDENSED IMIDAZOLE-BASED COMPOUND | EISAI CO LTD | 1991-10-22 | — | — | JP | disclosed |
| US-5053329-A | Aerobic culturing of actinoplanes yields hypotensive agent | MERCK & CO., INC. (US) | 1991-10-01 | — | — | US | disclosed |
| US-5053329-A | Aerobic culturing of actinoplanes yields hypotensive agent | MERCK & CO., INC. (US) | 1991-10-01 | — | — | US | disclosed |