Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161625 | 0.99 | AGTR1 (0.65) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL8972558 | 0.95 | AGTR2 (0.71) | AGTR1AGTR2 | |
| SCHEMBL8565683 | 0.94 | AGTR2 (0.72) | AGTR1AGTR2 | |
| Potassium SCHEMBL9649979 | 0.93 | AGTR2 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9406616 | 0.93 | AGTR2 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9406623 | 0.93 | AGTR2 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9649960 | 0.93 | AGTR2 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9539315 | 0.90 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8567083 | 0.90 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL7050680 | 0.90 | AGTR1 (0.55) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506238-A | HYPOTENSIVE AGENT | EISAI CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0628557-A1 | Biphenylmethane derivatives, the use of them and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328911-A | Cardiovascular disorders, hypotensive agents and congestive heart failure | EISAI CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0598702-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5298518-A | Biphenylmethane derivative and pharmacological use | EISAI CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |