Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895125 | 0.84 | KDM1A (0.49) | KDM1AMAOAMAOBMAPTSLC6A2 | |
| SCHEMBL25366114 | 0.82 | KDM1A (0.47) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL25367135 | 0.82 | MAOA (0.45) | KDM1AMAOAMAOBMAPTLMNA | |
| SCHEMBL8565737 | 0.81 | KDM1A (0.55) | KDM1AMAOAMAOBMAPTLMNA | |
| SCHEMBL25365036 | 0.80 | CTSV (0.52) | MAPTLMNAHPGD | |
| SCHEMBL25367668 | 0.80 | ALDH1A1 (0.51) | LMNAHPGDSLC6A2SLC6A3TSHR | |
| SCHEMBL9823890 | 0.79 | KDM1A (0.50) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL10514019 | 0.79 | FEN1 (0.43) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL8567016 | 0.78 | MAOA (0.45) | KDM1AMAOAMAOBMAPTLMNA | |
| SCHEMBL2893296 | 0.78 | GRIN2D (0.47) | KDM1AMAOAMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637438-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4402133-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | Enko Chem, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-118265704-A | Protoporphyrinogen oxidase inhibitors | 恩科化学公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| WO-2023044364-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637438-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, CYP4X1, CBR3 | KDM1A 1127/4885MAOA 269/4885MAOB 168/4885 |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PPIF, CYP4X1 | KDM1A 1164/4885MAOA 117/4885MAOB 98/4885 |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | KDM1A 1170/4885MAOA 114/4885MAOB 98/4885 |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | KDM1A 1164/4885MAOA 117/4885MAOB 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.