SCHEMBL85658

SCHEMBL85658

C=C(C)C(=O)OC(C(F)(F)F)(C(F)(F)F)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
EPHX1 P07099 2/20 0.32
HSD17B10 Q99714 1/20 0.32
GLA P06280 1/20 0.32
EPHX2 P34913 3/20 0.31
TSHR P16473 1/20 0.31
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85662 0.83 MEN1 (0.33) MEN1MAPK1KMT2AEPHX2
SCHEMBL15281488 0.79 CYP17A1 (0.36) ALDH1A1MEN1MAPK1KMT2AEPHX1
SCHEMBL677951 0.79 MEN1 (0.36) ALDH1A1MEN1MAPK1KMT2AEPHX1
SCHEMBL172055 0.79 CYP17A1 (0.36) ALDH1A1MEN1MAPK1KMT2AEPHX1
SCHEMBL19335554 0.78 MEN1 (0.38) ALDH1A1MEN1MAPK1KMT2AEPHX1
SCHEMBL1215028 0.75 MEN1 (0.33) ALDH1A1MEN1MAPK1KMT2AEPHX1
SCHEMBL1143209 0.75 EPHX2 (0.33) ALDH1A1MEN1MAPK1KMT2AEPHX2
SCHEMBL24908658 0.74 ALDH1A1 (0.33) ALDH1A1MEN1MAPK1KMT2AGLA
SCHEMBL1143635 0.74 EPHX2 (0.35) ALDH1A1MEN1MAPK1KMT2AEPHX2
SCHEMBL17754131 0.74 CYP19A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760010-B2 Patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-12 US disclosed
US-20160363866-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-12-15 US disclosed
US-9201300-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-12-01 US disclosed
US-20140178818-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-26 US disclosed
US-8129099-B2 Double patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20090208886-A1 DOUBLE PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-20 US disclosed