Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251944 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL8564301 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL8561932 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL8567685 | 0.81 | S100A4 (0.46) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL8567677 | 0.80 | KMT2A (0.50) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL8561208 | 0.79 | HPGD (0.43) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL20291524 | 0.79 | CYP3A4 (0.61) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL8563341 | 0.78 | MAPT (0.49) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL8567950 | 0.78 | CYP3A4 (0.47) | KDM4EALDH1A1GLASMN1; SMN2HSD17B10 | |
| SCHEMBL28013532 | 0.77 | S100A4 (0.54) | KDM4EALDH1A1GLASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |