Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567950 | 0.88 | CYP3A4 (0.47) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL3953291 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL8561932 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL8565807 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL8567685 | 0.83 | S100A4 (0.46) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL20291524 | 0.81 | CYP3A4 (0.61) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL8563341 | 0.81 | MAPT (0.49) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL12518927 | 0.80 | MAOA (0.48) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL8567514 | 0.80 | S100A4 (0.54) | KDM4EALDH1A1SMN1; SMN2GLAHPGD | |
| SCHEMBL8562456 | 0.80 | CYP3A4 (0.43) | KDM4EALDH1A1SMN1; SMN2GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |