Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL3204406 | 0.92 | CA12 (0.43) | TAAR1IDO1ALDH1A1LMNATP53 | |
| SCHEMBL2032776 | 0.89 | ALOX5 (0.49) | TAAR1IDO1ALDH1A1LMNATP53 | |
| SCHEMBL10874974 | 0.85 | TAAR1 (0.49) | TAAR1IDO1ALDH1A1LMNAMAPT | |
| SCHEMBL2921543 | 0.85 | IDO1 (0.47) | TAAR1IDO1ALDH1A1LMNATP53 | |
| SCHEMBL2939712 | 0.83 | GAA (0.40) | TAAR1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL11139082 | 0.83 | ALOX5 (0.49) | TAAR1IDO1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL7253568 | 0.81 | ALOX5 (0.47) | TAAR1IDO1ALDH1A1LMNATP53 | |
| SCHEMBL852646 | 0.80 | TAAR1 (0.64) | TAAR1IDO1ALDH1A1LMNAMAPT | |
| SCHEMBL29474956 | 0.80 | TAAR1 (0.64) | TAAR1IDO1ALDH1A1LMNAMAPT | |
| SCHEMBL15296216 | 0.79 | ALOX5 (0.45) | TAAR1IDO1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429614-B1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LTD (GB) | 1995-10-11 | — | — | EP | claimed |
| EP-0429614-A1 | AZOPHENYL COMPOUNDS. | JAMES ROBINSON LTD (GB) | 1991-06-05 | — | — | EP | claimed |
| WO-1990015850-A1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 1990-12-27 | — | — | WO | claimed |
| US-4757152-A | Process for producing indoles | RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) | 1988-07-12 | — | — | US | claimed |
| CN-1267431-C | Substituted quinazoline derivatives and their use as inhibitors | ASTRAZENECA AB (SE) | 2006-08-02 | — | — | CN | disclosed |
| US-5719270-A | DYES, INTERMEDIATES | PARTINGTON STEVEN MICHAEL (GB) | 1998-02-17 | — | — | US | disclosed |
| EP-0429614-B1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LTD (GB) | 1995-10-11 | — | — | EP | disclosed |
| EP-0182256-B1 | PROCESS FOR PRODUCING INDOLES | RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) | 1992-10-07 | — | — | EP | disclosed |
| EP-0429614-A1 | AZOPHENYL COMPOUNDS. | JAMES ROBINSON LTD (GB) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990015850-A1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 1990-12-27 | — | — | WO | disclosed |
| US-4757152-A | Process for producing indoles | RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0182256-A2 | Process for producing indoles | RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) | 1986-05-28 | — | — | EP | disclosed |