SCHEMBL2939712

SCHEMBL2939712

COc1ccc(CCO)c(N)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 2/20 0.40
MAPK1 P28482 2/20 0.40
HTT P42858 1/20 0.40
AOC3 Q16853 1/20 0.38
TAAR1 Q96RJ0 2/20 0.37
CYP19A1 P11511 2/20 0.37
ADRA1A P35348 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
NFKB1 P19838 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ATM Q13315 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
APEX1 P27695 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL1983735 0.92 SLC2A1 (0.40) GAATSHRMAPTMAPK1HTT
SCHEMBL18459025 0.87 GAA (0.37) GAATSHRMAPTMAPK1HTT
SCHEMBL8565816 0.83 TAAR1 (0.47) GAATSHRMAPTMAPK1AOC3
SCHEMBL9688670 0.78 AOC3 (0.50) AOC3
SCHEMBL1152190 0.77 TDP1 (0.48) GAATSHRMAPTHTTKDM4E
Sulfuric Acid SCHEMBL3204406 0.76 CA12 (0.43) MAPTMAPK1HTTAOC3TAAR1
SCHEMBL1710455 0.76 ALDH1A1 (0.50) GAATSHRMAPTMAPK1HTT
SCHEMBL1014275 0.76 ALDH1A1 (0.50) GAATSHRMAPTMAPK1HTT
SCHEMBL28003049 0.76 GAA (0.67) GAATSHRMAPTMAPK1HTT
SCHEMBL27685404 0.76 MAPT (0.52) GAATSHRMAPTMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923929-B1 KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS OXIDATION AGENTS, AND DYEING METHOD; PYRAZOLOAZOLES OREAL (FR) 2004-05-12 EP claimed
EP-0835093-B1 HAIR DYE AGENTS WITH AT LEAST ONE CONDITIONER HANS SCHWARZKOPF & HENKEL GMBH (DE) 2004-03-10 EP claimed
US-6228130-B1 1-(2,5-DIAMINOPHENYL)ETHYLENE GLYCOL; WATER SOLUBLE; P-PHENYLENEDIAMINE REPLACEMENT BRISTOL-MYERS SQUIBB COMPANY 2001-05-08 US claimed
EP-0835093-A1 HAIR DYE AGENTS WITH AT LEAST ONE CONDITIONER Hans Schwarzkopf GmbH & Co. KG (DE) 1998-04-15 EP claimed
WO-1997001323-A1 HAIR DYE AGENTS WITH AT LEAST ONE CONDITIONER HANS SCHWARZKOPF GMBH (DE) 1997-01-16 WO claimed
CN-122094655-A Second agent composition for hair cosmetics, hair cosmetics and hair cosmetic set 2026-05-26 CN disclosed
US-12485076-B2 Liquid hair dye composition KAO CORPORATION (JP) 2025-12-02 US disclosed
CN-114867447-B Multilayer soluble solid article comprising solid particles for preparing multilayer soluble solid article 宝洁公司 2024-11-29 CN disclosed
US-20240390244-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE SALT KAO CORPORATION (JP) 2024-11-28 US disclosed
CN-117794504-A Iris root extract, compositions and methods for dermatological use 捷通国际有限公司 2024-03-29 CN disclosed
CN-111989082-B Catalytic dye system ELC 管理有限责任公司 2023-10-31 CN disclosed
CN-111432885-B Cosmetic composition comprising a silicone material 美国陶氏有机硅公司 2023-09-29 CN disclosed
US-20010005914-A1 OXIDATION DYES ANDREAS J. BITTNER 2001-07-05 US disclosed
EP-0943319-A2 Hair-dye GOLDWELL GmbH (DE) 1999-09-22 EP disclosed
EP-0900206-A1 NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS L'OREAL (FR) 1999-03-10 EP disclosed
CN-1196673-A Keratin fibre dyeing composition containing pyrazolo-(1,5-alpha)-pyrimidine derivatives, dyeing method, pyrazolo-(1,5-alpha) pyrimidine new-type derivatives and preparation method thereof OREAL (FR) 1998-10-21 CN disclosed
EP-0858796-A2 Oxidative hair dye Wella Aktiengesellschaft (DE) 1998-08-19 EP disclosed
WO-1997042173-A1 NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS L'OREAL (FR) 1997-11-13 WO disclosed
CN-1134815-A Composition for oxidation dyeing of keratin fibres comprising combination of at least two specific para-phenylenediamine derivatives, and use thereof OREAL (FR) 1996-11-06 CN disclosed
EP-0593711-B1 METHOD FOR DYEING KERATIN FIBRES IN AN ALKALINE MEDIUM BY MEANS OF 2-SUBSTITUTED PARA-AMINOPHENOLS COMBINED WITH 6- OR 7-HYDROXYINDOLE, AND COMPOSITIONS THEREFOR OREAL (FR) 1996-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485076-B2 Liquid hair dye composition S100B, HLA-B, LDHB GAA 4531/4885TSHR 3997/4885MAPT 3771/4885
US-20010005914-A1 OXIDATION DYES AOC1, CBR3, KRT18 GAA 4430/4885TSHR 2959/4885MAPT 3633/4885
US-20240390244-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE SALT CS, SDHA, MDH2 GAA 1458/4885TSHR 4446/4885MAPT 1203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.