SCHEMBL8565835

SCHEMBL8565835

COc1c(C)c(C)c(OC)c(CCCI)c1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IMPDH1 P20839 3/20 0.31
IMPDH2 P12268 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9578870 0.94 IMPDH1 (0.32) IMPDH1IMPDH2
SCHEMBL10473241 0.81 ALOX5 (0.30)
SCHEMBL11097418 0.80 IMPDH1 (0.31) IMPDH1
SCHEMBL16067266 0.78 HTR2A (0.37) IMPDH1IMPDH2
SCHEMBL8564172 0.78 IMPDH2 (0.41) IMPDH1IMPDH2
SCHEMBL1784681 0.77 IMPDH1 (0.40) IMPDH1IMPDH2
SCHEMBL4964721 0.77 ALOX5 (0.47) IMPDH1
SCHEMBL4962807 0.77 ALOX5 (0.47) IMPDH1
SCHEMBL10596381 0.76 IMPDH1 (0.33) IMPDH1
SCHEMBL1820953 0.76 IMPDH2 (0.32) IMPDH1IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549366-B1 Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses SANKYO CO (JP) 1998-04-15 EP disclosed
CN-1032751-C thiazolidine compounds, their preparation and their therapeutic use SANKYO CO (JP) 1996-09-11 CN disclosed
EP-0549365-B1 Thiazolidine compounds, their preparation and their therapeutic uses SANKYO CO (JP) 1995-08-09 EP disclosed
US-5338855-A Treating diabetes or hyperlipemia SANKYO COMPANY, LIMITED (JP) 1994-08-16 US disclosed
CN-1074679-A Its preparation of thiazolidine compound and the therepic use thereof that contain quinonyl SANKYO CO (JP) 1993-07-28 CN disclosed
CN-1074680-A Thiazolidine compound, its preparation and therepic use thereof SANKYO CO (JP) 1993-07-28 CN disclosed
EP-0549366-A1 Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-06-30 EP disclosed
EP-0549365-A1 Thiazolidine compounds, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-06-30 EP disclosed