Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 7/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 4/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784681 | 0.94 | IMPDH1 (0.40) | IMPDH2IMPDH1TNKS2LMNAPGR | |
| SCHEMBL8563125 | 0.89 | IMPDH2 (0.49) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL1242706 | 0.87 | TNKS2 (0.35) | IMPDH2IMPDH1TNKS2LMNAPGR | |
| SCHEMBL19463178 | 0.81 | TNKS2 (0.42) | IMPDH2IMPDH1TNKS2LMNAPGR | |
| SCHEMBL11098325 | 0.81 | LMNA (0.40) | IMPDH2IMPDH1TNKS2LMNAPGR | |
| SCHEMBL9549629 | 0.79 | CA2 (0.46) | IMPDH2IMPDH1MAPTCA2CA4 | |
| SCHEMBL24783641 | 0.79 | LMNA (0.42) | IMPDH2IMPDH1LMNAPGRCYP3A4 | |
| SCHEMBL22172495 | 0.79 | LMNA (0.42) | IMPDH2IMPDH1LMNAPGRCYP3A4 | |
| SCHEMBL24784363 | 0.79 | LMNA (0.42) | IMPDH2IMPDH1LMNAPGRCYP3A4 | |
| SCHEMBL8565835 | 0.78 | IMPDH1 (0.31) | IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11692008-B2 | Preparation and uses of reactive oxygen species scavenger derivatives | XWPharma Ltd. (KY) | 2023-07-04 | — | — | US | disclosed |
| US-11692008-B2 | Preparation and uses of reactive oxygen species scavenger derivatives | XWPharma Ltd. (KY) | 2023-07-04 | — | — | US | disclosed |
| US-11692008-B2 | Preparation and uses of reactive oxygen species scavenger derivatives | XWPharma Ltd. (KY) | 2023-07-04 | — | — | US | disclosed |
| CN-115109116-A | Preparation and use of active oxygen scavenger derivatives | 凯瑞康宁生物工程（武汉）有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-111278807-B | Preparation and use of active oxygen scavenger derivatives | 凯瑞康宁生物工程（武汉）有限公司 | 2022-07-22 | — | — | CN | disclosed |
| EP-3668837-B1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XWPHARMA LTD (KY) | 2022-07-06 | — | — | EP | disclosed |
| EP-3668837-B1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XWPHARMA LTD (KY) | 2022-07-06 | — | — | EP | disclosed |
| US-20210047367-A1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XWPharma Ltd. (KY) | 2021-02-18 | — | — | US | disclosed |
| US-20210047367-A1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XWPharma Ltd. (KY) | 2021-02-18 | — | — | US | disclosed |
| US-10858394-B2 | Preparation and uses of reactive oxygen species scavenger derivatives | XW LABORATORIES INC. (KY) | 2020-12-08 | — | — | US | disclosed |
| US-20200181194-A1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XWPharma Ltd. (KY) | 2020-06-11 | — | — | US | disclosed |
| WO-2019033330-A1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XW LABORATORIES, INC. (CN) | 2019-02-21 | — | — | WO | disclosed |
| WO-2015155234-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | NICOX SCIENCE IRELAND (IE) | 2015-10-15 | — | — | WO | disclosed |
| WO-2015155234-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | NICOX SCIENCE IRELAND (IE) | 2015-10-15 | — | — | WO | disclosed |
| EP-0549366-B1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-04-15 | — | — | EP | disclosed |
| CN-1033639-C | Benzoquinonyl-containing thiazolidine compound, preparing process thereof and its application in medicine | SANKYO CO (JP) | 1996-12-25 | — | — | CN | disclosed |
| EP-0549365-B1 | Thiazolidine compounds, their preparation and their therapeutic uses | SANKYO CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5338855-A | Treating diabetes or hyperlipemia | SANKYO COMPANY, LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0549366-A1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0549365-A1 | Thiazolidine compounds, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181194-A1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | AIFM2, GPX1, GPX4 | IMPDH2 1961/4885IMPDH1 1797/4885TNKS2 3314/4885 |
| US-20210047367-A1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | AIFM2, GPX1, GPX4 | IMPDH2 1961/4885IMPDH1 1797/4885TNKS2 3314/4885 |
| US-11692008-B2 | Preparation and uses of reactive oxygen species scavenger derivatives | AIFM2, GPX1, GPX4 | IMPDH2 1961/4885IMPDH1 1797/4885TNKS2 3314/4885 |
| US-10858394-B2 | Preparation and uses of reactive oxygen species scavenger derivatives | AIFM2, GPX1, GPX4 | IMPDH2 1961/4885IMPDH1 1797/4885TNKS2 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.