Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112657 | 1.00 | GABRA1 (0.42) | GABRA1GABRB2LIPGADRB2ADRB1 | |
| SCHEMBL10880026 | 1.00 | GABRA1 (0.42) | GABRA1GABRB2LIPGADRB2ADRB1 | |
| SCHEMBL8567596 | 1.00 | GABRA1 (0.42) | GABRA1GABRB2LIPGADRB2ADRB1 | |
| SCHEMBL8123791 | 0.98 | GABRA1 (0.44) | GABRA1GABRB2LIPGADRB2ADRB1 | |
| SCHEMBL8128253 | 0.92 | GABRA1 (0.45) | GABRA1GABRB2LIPGSIGMAR1 | |
| SCHEMBL8124571 | 0.84 | GABRA1 (0.48) | GABRA1GABRB2SIGMAR1 | |
| SCHEMBL28065380 | 0.81 | LIPG (0.52) | GABRA1GABRB2LIPGCYSLTR2CYSLTR1 | |
| SCHEMBL9715937 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2SIGMAR1 | |
| SCHEMBL11647220 | 0.79 | LIPG (0.58) | LIPGTHRATHRBCYSLTR2CYSLTR1 | |
| SCHEMBL7649388 | 0.79 | LIPG (0.48) | LIPGTHRATHRBCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717742-B1 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5780633-A | Process for the preparation of indolizine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0717742-A1 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007279-A2 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |
| US-5334716-A | Preventing testosteron 5a-reductase mediated diseases; alopecia, acne, prostatism | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0519353-A2 | Indolizin derivatives, process for their preparation and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |