Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983505 | 1.00 | LIPG (0.47) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL17802345 | 1.00 | LIPG (0.47) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL981932 | 0.98 | LIPG (0.45) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL982519 | 0.93 | LIPG (0.39) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL983255 | 0.86 | SREBF2 (0.33) | LIPGPPARAPPARGMAPT | |
| SCHEMBL12815176 | 0.79 | LIPG (0.46) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL5271436 | 0.79 | LIPG (0.46) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL8519841 | 0.79 | LIPG (0.46) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL982140 | 0.79 | GABRA1 (0.35) | TP53MAPTKMT2A | |
| SCHEMBL9400761 | 0.78 | LIPG (0.47) | LIPGBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821675-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033176-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |