Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566254 | 0.84 | IKBKB (0.42) | LMNAMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL8629459 | 0.80 | CYP19A1 (0.39) | CYP19A1LMNAMEN1KMT2AHTT | |
| SCHEMBL8601222 | 0.80 | MAPT (0.42) | CYP19A1LMNAMEN1KMT2ATLR8 | |
| SCHEMBL14764478 | 0.80 | MEN1 (0.54) | LMNAMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL29871162 | 0.80 | MEN1 (0.54) | LMNAMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL8601051 | 0.79 | ALDH1A1 (0.49) | LMNANPC1RAB9AALDH1A1POLB | |
| SCHEMBL8601080 | 0.78 | HTT (0.43) | LMNAMEN1KMT2AHTTTLR8 | |
| SCHEMBL5038254 | 0.78 | CYP11B1 (0.50) | CYP19A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL8599555 | 0.77 | CNR1 (0.42) | CYP19A1LMNAMEN1KMT2AHTT | |
| SCHEMBL5145767 | 0.77 | MAPT (0.47) | LMNAMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |