Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241091 | 0.78 | ALDH1A1 (0.39) | SLC1A1SLC1A3SLC1A2ALDH1A1PKM | |
| SCHEMBL9241102 | 0.78 | ALDH1A1 (0.39) | SLC1A1SLC1A3SLC1A2ALDH1A1PKM | |
| SCHEMBL8556971 | 0.76 | SLC1A1 (0.41) | SLC1A1SLC1A3SLC1A2PKMALPI | |
| SCHEMBL11380644 | 0.74 | ALDH1A1 (0.49) | ALDH1A1PKMPOLBGAATSHR | |
| SCHEMBL8558691 | 0.70 | GRM2 (0.49) | SLC1A1SLC1A3SLC1A2PKMALPI | |
| SCHEMBL8566832 | 0.65 | HSD17B10 (0.44) | ALDH1A1SLC7A5POLBGAATSHR | |
| SCHEMBL8566839 | 0.65 | HSD17B10 (0.44) | ALDH1A1SLC7A5POLBGAATSHR | |
| SCHEMBL8564931 | 0.65 | GRM2 (0.39) | SLC1A1SLC1A3SLC1A2PKMALPI | |
| SCHEMBL8564937 | 0.65 | GRM2 (0.39) | SLC1A1SLC1A3SLC1A2PKMALPI | |
| SCHEMBL10397191 | 0.64 | CYP11B1 (0.55) | SLC1A1SLC1A3SLC1A2PKMALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |