Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566392 | 1.00 | DRD1 (0.38) | DRD1GRM5AKR1C3LIPESPR | |
| SCHEMBL8567905 | 1.00 | DRD1 (0.38) | DRD1GRM5AKR1C3LIPESPR | |
| SCHEMBL15672478 | 0.85 | DRD1 (0.36) | DRD1GRM5AKR1C3LIPESPR | |
| SCHEMBL8570891 | 0.85 | DRD1 (0.37) | DRD1GRM5AKR1C3LIPESPR | |
| SCHEMBL8571174 | 0.84 | DRD1 (0.40) | DRD1GRM5AKR1C3LIPESPR | |
| SCHEMBL8572810 | 0.84 | DRD1 (0.40) | DRD1GRM5AKR1C3LIPESPR | |
| SCHEMBL8571176 | 0.84 | DRD1 (0.40) | DRD1GRM5AKR1C3LIPESPR | |
| SCHEMBL8572844 | 0.83 | SPR (0.41) | DRD1GRM5AKR1C3SPRMAPK1 | |
| SCHEMBL8572580 | 0.79 | ALDH1A1 (0.36) | DRD1GRM5AKR1C3LIPETRPM8 | |
| Hydrochloric Acid SCHEMBL8566799 | 0.77 | PRCP (0.33) | DRD1AKR1C3MAPK1PRCPTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |