Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | SPR | P35270 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568770 | 0.86 | DRD1 (0.40) | DRD1PRCPMAPK1HTR1APRMT5 | |
| SCHEMBL8566400 | 0.85 | DRD1 (0.38) | DRD1PRCPMAPK1GRM5SPR | |
| SCHEMBL8567905 | 0.85 | DRD1 (0.38) | DRD1PRCPMAPK1GRM5SPR | |
| SCHEMBL8566392 | 0.85 | DRD1 (0.38) | DRD1PRCPMAPK1GRM5SPR | |
| SCHEMBL8572994 | 0.81 | GRIN2D (0.39) | DRD1PRCPGRM5HTR1APRMT5 | |
| SCHEMBL8572844 | 0.79 | SPR (0.41) | DRD1MAPK1GRM5SPRAKR1C3 | |
| SCHEMBL6989000 | 0.78 | DRD1 (0.39) | DRD1PRCPMAPK1HTR1APRMT5 | |
| SCHEMBL8572580 | 0.75 | ALDH1A1 (0.36) | DRD1GRM5AKR1C3LIPE | |
| Hydrochloric Acid SCHEMBL8568119 | 0.74 | RXFP1 (0.35) | OPRM1 | |
| SCHEMBL15672478 | 0.74 | DRD1 (0.36) | DRD1PRCPMAPK1GRM5SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |