Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600211 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1MAPTMEN1 | |
| SCHEMBL8564988 | 0.80 | LTB4R (0.45) | POLBALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL8565715 | 0.79 | KMT2A (0.46) | POLBALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL8567246 | 0.77 | MAPT (0.45) | POLBALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL8563057 | 0.77 | POLB (0.46) | POLBALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL8600823 | 0.75 | KMT2A (0.43) | POLBALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL28232869 | 0.73 | ALDH1A1 (0.66) | POLBALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL8560017 | 0.73 | CYP1A2 (0.51) | POLBALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL8567732 | 0.73 | MAPT (0.45) | POLBALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL8567734 | 0.73 | MAPT (0.45) | POLBALDH1A1SMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |