Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567246 | 0.83 | MAPT (0.45) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL8600823 | 0.81 | KMT2A (0.43) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL8600211 | 0.79 | ALDH1A1 (0.55) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL8566432 | 0.79 | POLB (0.45) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL3298254 | 0.77 | KMT2A (0.54) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL8566524 | 0.76 | MEN1 (0.53) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL8561151 | 0.76 | BACE1 (0.51) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL483953 | 0.76 | CTSB (0.50) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL28232869 | 0.76 | ALDH1A1 (0.66) | KMT2AMAPTMEN1RAB9AMAPK1 | |
| SCHEMBL8562475 | 0.76 | KMT2A (0.49) | KMT2AMAPTMEN1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |