Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569113 | 0.82 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL8571445 | 0.76 | ALDH1A1 (0.43) | FABP7FABP5CHRM5CHRM1CHRM3 | |
| SCHEMBL8568639 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL3732372 | 0.71 | ALDH1A1 (0.59) | MAPTKMT2AALDH1A1 | |
| SCHEMBL26023562 | 0.70 | MAPT (0.68) | CHRM5CHRM1CHRM3MAPTATM | |
| SCHEMBL305162 | 0.70 | MAPT (0.68) | CHRM5CHRM1CHRM3MAPTATM | |
| SCHEMBL16321874 | 0.69 | ALDH1A1 (0.57) | FABP7FABP5MAPTATMKMT2A | |
| SCHEMBL2842512 | 0.69 | KMT2A (0.71) | FABP7FABP5MAPTATMKMT2A | |
| SCHEMBL3727515 | 0.69 | FFAR1 (0.60) | FABP7FABP5ATMKMT2AALDH1A1 | |
| SCHEMBL5689482 | 0.68 | ALDH1A1 (0.67) | MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35865-E | Preparation of glutaric acid derivatives | PFIZER INC. (US) | 1998-07-28 | — | — | US | disclosed |
| US-5714628-A | CARBOXYLATION A CYCLOHEXANONES TO A CYCLOPENTANECARBOXYLIC ACIDS WITH HYDROGEN PEROXIDE | PFIZER, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0391673-B2 | Preparation of glutaric acid derivatives | PFIZER LTD (GB) | 1997-04-02 | — | — | EP | disclosed |
| US-5166406-A | Peroxidation of cyclohexanone derivatives | PFIZER INC. (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0391673-A1 | Preparation of glutaric acid derivatives | Pfizer Limited (GB) | 1990-10-10 | — | — | EP | disclosed |