Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569113 | 0.85 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8570425 | 0.78 | RAB9A (0.49) | ALDH1A1L3MBTL1MAPK1RAB9AMAPT | |
| SCHEMBL8572306 | 0.76 | PARP1 (0.36) | ALDH1A1GAA | |
| SCHEMBL28374567 | 0.72 | BCL9 (0.63) | ALDH1A1L3MBTL1MAPK1RAB9AMAPT | |
| SCHEMBL15388876 | 0.72 | RAB9A (0.61) | ALDH1A1L3MBTL1MAPK1RAB9AMAPT | |
| SCHEMBL8566451 | 0.72 | FABP7 (0.41) | ALDH1A1MAPT | |
| SCHEMBL12814849 | 0.71 | RAB9A (0.60) | ALDH1A1L3MBTL1MAPK1RAB9AMAPT | |
| SCHEMBL8830793 | 0.71 | TACR1 (0.41) | ALDH1A1RAB9AMAPTPOLB | |
| SCHEMBL8565163 | 0.70 | TP53 (0.30) | — | |
| SCHEMBL17775400 | 0.70 | PTPN1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35865-E | Preparation of glutaric acid derivatives | PFIZER INC. (US) | 1998-07-28 | — | — | US | disclosed |
| US-5714628-A | CARBOXYLATION A CYCLOHEXANONES TO A CYCLOPENTANECARBOXYLIC ACIDS WITH HYDROGEN PEROXIDE | PFIZER, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0391673-B2 | Preparation of glutaric acid derivatives | PFIZER LTD (GB) | 1997-04-02 | — | — | EP | disclosed |
| US-5166406-A | Peroxidation of cyclohexanone derivatives | PFIZER INC. (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0391673-A1 | Preparation of glutaric acid derivatives | Pfizer Limited (GB) | 1990-10-10 | — | — | EP | disclosed |